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The Functional Breeding Podcast is about how to breed dogs for function and for health, behavioral and physical. It is brought to you by the Functional Dog Collaborative, a non-profit organization founded to support the ethical breeding of healthy, behaviorally sound dogs. The FDC’s goals include providing educational, social, and technical resources to breeders of both purebred and mixed breed dogs, helping us all learn more about how to breed good companions who are fit for sports or work. You can find out more at functionalbreeding.org or at the Functional Breeding facebook group, which is a friendly and inclusive community.
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5 days ago
5 days ago
This episode is just me (Jessica Perry Hekman, DVM, PhD) - talking about a new genetic test for the risk of mitral valve disease in Cavalier King Charles Spaniels. Cavs are at incredibly high risk of this disease and get it at much younger ages than other breeds. What does this new test mean in terms of predicting if your Cav is at risk, and whether a particular Cav should be bred?
I talk about several papers in this episode. If you want to check them out yourself, they are:
- Mead, Sophie E., et al. "Genetic Variants at the Nebulette Locus Are Associated with Myxomatous Mitral Valve Disease Severity in Cavalier King Charles Spaniels." Genes 13.12 (2022): 2292. - https://pmc.ncbi.nlm.nih.gov/articles/PMC9778376/
- Mattin, M. J., et al. "Prevalence of and risk factors for degenerative mitral valve disease in dogs attending primary‐care veterinary practices in England." Journal of Veterinary Internal Medicine 29.3 (2015): 847-854. - https://onlinelibrary.wiley.com/doi/full/10.1111/jvim.12591
- Keene, Bruce W., et al. "ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs." Journal of veterinary internal medicine 33.3 (2019): 1127-1140. - https://pmc.ncbi.nlm.nih.gov/articles/PMC6524084/
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